Cirrhotic cardiomyopathy: An independent prognostic factor for cirrhotic patients

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Cirrhotic cardiomyopathy.

Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction, and 7% to 21% of deaths after orthotopic li...

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Cirrhotic cardiomyopathy

Cardiomyopathy is a chronic disease of the myocardium characterized by an abnormal dilatation and thinning of the left ventricular (LV), associated with the contractile dysfunction of the muscle and loss of pump capacity, resulting in the occurrence of arrhythmias and myocardial infarction. It has many causes and can occur in the liver pathology inclusively.

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Cirrhotic cardiomyopathy.

During the course of cirrhosis, there is a progressive deterioration of cardiac function manifested by the disappearance of the hyperdynamic circulation due to a failure in heart function with decreased cardiac output. This is due to a deterioration in inotropic and chronotropic function which takes place in parallel with a diastolic dysfunction and cardiac hypertrophy in the absence of other k...

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Cirrhotic cardiomyopathy

Most patients with liver cirrhosis have hyperdynamic circulatory alterations with increased cardiac output, and decreased systemic vascular resistance and arterial pressure. But, in spite of the increased resting cardiac output, ventricular contractile response to stressful stimuli is attenuated in cirrhotic patients which is termed as cirrhotic cardiomyopathy. The prevalence of cirrhotic cardi...

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The Model for End-Stage Liver Disease score: an independent prognostic factor of mortality in injured cirrhotic patients.

OBJECTIVE To examine the ability of the model for end-stage liver disease (MELD) score to predict the risk of mortality in trauma patients with cirrhosis. Although cirrhosis is associated with poor outcomes after injury, the relative effect of the severity of the cirrhosis on outcomes is unclear. The MELD score is a prospectively developed and validated scoring system, which is associated with ...

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ژورنال

عنوان ژورنال: Clinical and Molecular Hepatology

سال: 2018

ISSN: 2287-2728,2287-285X

DOI: 10.3350/cmh.2018.0098